Nephrotic syndrome in adults: symptoms and management

Nephrotic syndrome in adults: diagnosis and management.

Nephrotic syndrome may be caused by primary (idiopathic) renal disease or by a variety of secondary causes. Patients present with marked edema, proteinuria, hypoalbuminemia, and often hyperlipidemia. In adults, diabetes mellitus is the most common secondary cause, and focal segmental glomerulosclerosis and membranous nephropathy are the most common primary causes. Venous thromboembolism is a po...

Diagnosis and Management of Nephrotic Syndrome in Adults.

Nephrotic syndrome (NS) consists of peripheral edema, heavy proteinuria, and hypoalbuminemia, often with hyperlipidemia. Patients typically present with edema and fatigue, without evidence of heart failure or severe liver disease. The diagnosis of NS is based on typical clinical features with confirmation of heavy proteinuria and hypoalbuminemia. The patient history and selected diagnostic stud...

Nephrotic syndrome: pathogenesis and management.

Management of the nephrotic syndrome.

(1) Congenital nephrosis. A group of disorders present at and presenting soon after birth, which are familial and may be acquired or inherited. Persistent oedema attracts attention in the first weeks of life. The disease may be rapidly lethal, but occasionally the patient will survive for a year or more without fatal infection or lethal azotaemia. The disease pattern tends to run true within a ...

FK 506 in the management of transplant-related nephrotic syndrome and steroid-resistant nephrotic syndrome.

N EPHROTIC syndrome is a broad group of disorders with diverse etiologies. In common. all have proteinuria. edema. hypercholesterolemia. and hypoalbuminemia. Steroids have proven effective in some histologic groups. but many are resistant to steroids and progress to end-stage renal disease. Transplant glomerulopathy and chronic rejection also contribute heavily to renal transplant-related nephr...